Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Lo, R.; Turner, M.S.; Barry, D.G.; Sreekumar, R.; Walsh, T.P.; Giffard, P.M.
    Cystathionine {gamma}-lyase is a component of cystine-mediated oxidative defense in Lactobacillus reuteri BR11 (2009), J. Bacteriol., 191, 1827-1837.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.4.1.1 expressed in Escherichia coli Limosilactobacillus reuteri

Protein Variants

EC Number Protein Variants Comment Organism
4.4.1.1 additional information PNG902 and PNG903 strains (cgl, cyuC and mlp mutants), constructing a cgl mutant (PNG901) and comparing it to a similarly constructed cyuC mutant (PNG902). The growth defects in aerated cultures of both mutants are alleviated by supplementation with cysteine (and cystine in the cgl mutant) but not methionine, with the cyuC mutant showing a much higher requirement Limosilactobacillus reuteri

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Limosilactobacillus reuteri
-
 BR11
-
4.4.1.1 Limosilactobacillus reuteri BR11
-
 BR11
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 L-cystine + H2O
-
 Limosilactobacillus reuteri NH3 + pyruvate + L-thiocysteine
-
 ?
4.4.1.1 L-cystine + H2O
-
 Limosilactobacillus reuteri BR11 NH3 + pyruvate + L-thiocysteine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.4.1.1 cgl
-
 Limosilactobacillus reuteri
4.4.1.1 cystathionine gamma-lyase
-
 Limosilactobacillus reuteri

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.1 pyridoxal 5'-phosphate
-
 Limosilactobacillus reuteri