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Literature summary extracted from

  • Landete, J.M.; Pardo, I.; Ferrer, S.
    Regulation of hdc expression and HDC activity by enological factors in lactic acid bacteria (2008), J. Appl. Microbiol., 105, 1544-1551.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.22 ethanol does not increase hdc gene expression or activity in cells, but increases HDC activity Oenococcus oeni
4.1.1.22 ethanol does not increase hdc gene expression or activity in cells, but increases HDC activity Pediococcus parvulus
4.1.1.22 ethanol does not increase hdc gene expression or activity in cells, but increases HDC activity, 122% activity at 10% ethanol Lentilactobacillus hilgardii
4.1.1.22 additional information tartaric acid, L-lactic acid, and sulfur dioxide have no effect on enzyme synthesis and activity Oenococcus oeni
4.1.1.22 additional information tartaric acid, L-lactic acid, and sulfur dioxide have no effect on enzyme synthesis and activity Lentilactobacillus hilgardii
4.1.1.22 additional information tartaric acid, L-lactic acid, and sulfur dioxide have no effect on enzyme synthesis and activity Pediococcus parvulus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.22 Citric acid diminishes hdc gene expression Oenococcus oeni
4.1.1.22 Citric acid diminishes hdc gene expression Pediococcus parvulus
4.1.1.22 D-fructose diminishes hdc gene expression Oenococcus oeni
4.1.1.22 D-fructose diminishes hdc gene expression Pediococcus parvulus
4.1.1.22 D-glucose diminishes hdc gene expression Oenococcus oeni
4.1.1.22 D-glucose diminishes hdc gene expression Pediococcus parvulus
4.1.1.22 L-Citric acid 19% hdc gene expression at 0.8 g/l Lentilactobacillus hilgardii
4.1.1.22 L-Fructose 46% hdc gene expression at 50 g/l Lentilactobacillus hilgardii
4.1.1.22 L-Glucose 22% hdc gene expression at 50 g/l Lentilactobacillus hilgardii
4.1.1.22 L-Malic acid 26% hdc gene expression at 4 g/l Lentilactobacillus hilgardii
4.1.1.22 malic acid diminishes hdc gene expression Oenococcus oeni
4.1.1.22 malic acid diminishes hdc gene expression Pediococcus parvulus

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.22 Lentilactobacillus hilgardii
-
-
-
4.1.1.22 Lentilactobacillus hilgardii 464
-
-
-
4.1.1.22 Oenococcus oeni
-
-
-
4.1.1.22 Oenococcus oeni 4042
-
-
-
4.1.1.22 Pediococcus parvulus
-
-
-
4.1.1.22 Pediococcus parvulus P270
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.22 L-histidine
-
 Oenococcus oeni histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Lentilactobacillus hilgardii histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Pediococcus parvulus histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Pediococcus parvulus P270 histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Lentilactobacillus hilgardii 464 histamine + CO2
-
 ?
4.1.1.22 L-histidine
-
 Oenococcus oeni 4042 histamine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.22 HDC
-
 Oenococcus oeni
4.1.1.22 HDC
-
 Lentilactobacillus hilgardii
4.1.1.22 HDC
-
 Pediococcus parvulus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.22 28
-
-
 Oenococcus oeni
4.1.1.22 28
-
-
 Lentilactobacillus hilgardii
4.1.1.22 28
-
-
 Pediococcus parvulus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
4.1.1.22 4 50 HDC activity is very low at 4 and 50°C Oenococcus oeni
4.1.1.22 4 50 HDC activity is very low at 4 and 50°C Lentilactobacillus hilgardii
4.1.1.22 4 50 HDC activity is very low at 4 and 50°C Pediococcus parvulus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.22 8
-
-
 Oenococcus oeni
4.1.1.22 8
-
-
 Lentilactobacillus hilgardii
4.1.1.22 8
-
-
 Pediococcus parvulus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
4.1.1.22 8.5
-
 activity drops by 86% at pH 8.5 Oenococcus oeni
4.1.1.22 8.5
-
 activity drops by 86% at pH 8.5 Lentilactobacillus hilgardii
4.1.1.22 8.5
-
 activity drops by 86% at pH 8.5 Pediococcus parvulus

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.22 pyridoxal 5'-phosphate
-
 Oenococcus oeni
4.1.1.22 pyridoxal 5'-phosphate
-
 Lentilactobacillus hilgardii
4.1.1.22 pyridoxal 5'-phosphate
-
 Pediococcus parvulus