EC Number | Cloned (Comment) | Organism |
---|---|---|
1.1.1.315 | - |
Mus musculus |
1.1.1.315 | - |
Bos taurus |
1.1.1.315 | RDH10 is expressed in COS cells | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.1.1.315 | microsome | - |
Homo sapiens | - |
- |
1.1.1.315 | microsome | - |
Mus musculus | - |
- |
1.1.1.315 | microsome | - |
Bos taurus | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.1.1.315 | 38087 | - |
x * 38087, calculated from sequence | Homo sapiens |
1.1.1.315 | 38090 | - |
calculated from sequence | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.315 | Bos taurus | Q8HZT6 | - |
- |
1.1.1.315 | Homo sapiens | Q8IZV5 | - |
- |
1.1.1.315 | Mus musculus | Q8VCH7 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.315 | brain | low activity | Bos taurus | - |
1.1.1.315 | kidney | low activity | Bos taurus | - |
1.1.1.315 | liver | low activity | Bos taurus | - |
1.1.1.315 | lung | low activity | Bos taurus | - |
1.1.1.315 | pancreas | low activity | Bos taurus | - |
1.1.1.315 | retinal pigment epithelium | - |
Homo sapiens | - |
1.1.1.315 | retinal pigment epithelium | - |
Mus musculus | - |
1.1.1.315 | retinal pigment epithelium | high activity | Bos taurus | - |
1.1.1.315 | skeletal muscle | low activity | Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.315 | all-trans-retinol + NAD+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor. At assay conditions (pH 5.5 and pH 7.6), and NADH or NADPH is used as the cofactor, only a low level of all-trans retinol is generated by RDH10 | Homo sapiens | all-trans-retinal + NADH + H+ | - |
r | |
1.1.1.315 | all-trans-retinol + NAD+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor. At assay conditions (pH 5.5 and pH 7.6), and NADH or NADPH is used as the cofactor, only a low level of all-trans retinol is generated by RDH10 | Mus musculus | all-trans-retinal + NADH + H+ | - |
r | |
1.1.1.315 | all-trans-retinol + NAD+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor. At assay conditions (pH 5.5 and pH 7.6), and NADH or NADPH is used as the cofactor, only a low level of all-trans retinol is generated by RDH10 | Bos taurus | all-trans-retinal + NADH + H+ | - |
r | |
1.1.1.315 | all-trans-retinol + NADP+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor. At assay conditions (pH 5.5 and pH 7.6), and NADH or NADPH is used as the cofactor, only a low level of all-trans retinol is generated by RDH10 | Homo sapiens | all-trans-retinal + NADPH + H+ | - |
r | |
1.1.1.315 | all-trans-retinol + NADP+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor. At assay conditions (pH 5.5 and pH 7.6), and NADH or NADPH is used as the cofactor, only a low level of all-trans retinol is generated by RDH10 | Mus musculus | all-trans-retinal + NADPH + H+ | - |
r | |
1.1.1.315 | all-trans-retinol + NADP+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor. At assay conditions (pH 5.5 and pH 7.6), and NADH or NADPH is used as the cofactor, only a low level of all-trans retinol is generated by RDH10 | Bos taurus | all-trans-retinal + NADPH + H+ | - |
r | |
1.1.1.315 | additional information | RDH10 does not oxidize 11-cis retinol, 9-cis retinol, or 13-cis retinol into the respective retinal (pH 7.6, in the presence of NAD or NADP+), indicating the substrate specificity of RDH10 | Homo sapiens | ? | - |
? | |
1.1.1.315 | additional information | RDH10 does not oxidize 11-cis retinol, 9-cis retinol, or 13-cis retinol into the respective retinal (pH 7.6, in the presence of NAD or NADP+), indicating the substrate specificity of RDH10 | Mus musculus | ? | - |
? | |
1.1.1.315 | additional information | RDH10 does not oxidize 11-cis retinol, 9-cis retinol, or 13-cis retinol into the respective retinal (pH 7.6, in the presence of NAD or NADP+), indicating the substrate specificity of RDH10 | Bos taurus | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.1.1.315 | ? | x * 38087, calculated from sequence | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.1.1.315 | atRDH | - |
Homo sapiens |
1.1.1.315 | atRDH | - |
Mus musculus |
1.1.1.315 | atRDH | - |
Bos taurus |
1.1.1.315 | RDH10 | - |
Homo sapiens |
1.1.1.315 | RDH10 | - |
Mus musculus |
1.1.1.315 | RDH10 | - |
Bos taurus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.315 | NAD+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor | Mus musculus | |
1.1.1.315 | NAD+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor | Bos taurus | |
1.1.1.315 | NAD+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP+ as the cofactor | Homo sapiens | |
1.1.1.315 | NADH | - |
Homo sapiens | |
1.1.1.315 | NADH | - |
Mus musculus | |
1.1.1.315 | NADH | - |
Bos taurus | |
1.1.1.315 | NADP+ | the addition of NADP+ resulted in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP+ as the cofactor | Homo sapiens | |
1.1.1.315 | NADP+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor | Mus musculus | |
1.1.1.315 | NADP+ | the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor | Bos taurus | |
1.1.1.315 | NADPH | - |
Homo sapiens | |
1.1.1.315 | NADPH | - |
Mus musculus | |
1.1.1.315 | NADPH | - |
Bos taurus |
EC Number | Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|---|
1.1.1.315 | Homo sapiens | calculated from sequence | - |
7.4 |