Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Lopez-Lazaro, M.; Willmore, E.; Elliott, S.L.; Austin, C.A.
    Selenite induces topoisomerase I and II-DNA complexes in K562 leukemia cells (2008), Int. J. Cancer, 123, 2217-2221.
    View publication on PubMed

Application

EC Number Application Comment Organism
5.6.2.1 drug development enzyme is target of several anticancer drugs Homo sapiens
5.6.2.2 drug development enzyme is target of several useful anticancer drugs Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.6.2.1 Selenite selenite induces topoisomerase I-DNA complexes in K562 cells Homo sapiens
5.6.2.2 Selenite selenite induces topoisomerase II-DNA complexes in K562 cells Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
5.6.2.1 Homo sapiens
-
-
-
5.6.2.2 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.2.1 K-562 cell K562 leukemia cell Homo sapiens
-
5.6.2.2 K-562 cell K-562 leukemia cell Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
5.6.2.1 DNA topoisomerase I
-
 Homo sapiens
5.6.2.1 Topo I
-
 Homo sapiens
5.6.2.1 Topoisomerase I
-
 Homo sapiens
5.6.2.2 DNA topoisomerase II
-
 Homo sapiens
5.6.2.2 topo II
-
 Homo sapiens
5.6.2.2 Topoisomerase II
-
 Homo sapiens