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Literature summary extracted from

  • Ivessa, A.S.; Zhou, J.Q.; Schulz, V.P.; Monson, E.K.; Zakian, V.A.
    Saccharomyces Rrm3p, a 5' to 3' DNA helicase that promotes replication fork progression through telomeric and subtelomeric DNA (2002), Genes Dev., 16, 1383-1396.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.6.2.3 single-stranded DNA stimulates Saccharomyces cerevisiae

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.6.2.3 expression of a truncated version of Rrm3p as a GST fusion protein in Saccharomyces cerevisiae. This polypeptide (Rrm3pDELTAN), contains amino acids 194 to 723 of the 723-amino-acid protein, including all seven helicase motifs as well as 56 amino acids amino-terminal of the first helicase motif. Rrm3pDELTAN is expressed under the control of a galactose-inducible promoter Saccharomyces cerevisiae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
5.6.2.3 Mg2+ required Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.2.3 ATP + H2O Saccharomyces cerevisiae 5' to 3' DNA helicase. The ATPase/helicase activity of Rrm3p is required for its role in telomeric and subtelomeric DNA replication. Because Rrm3p is telomere-associated in vivo, it likely has a direct role in telomere replication ADP + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.2.3 Saccharomyces cerevisiae P07271
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.6.2.3
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.2.3 ATP + H2O
-
 Saccharomyces cerevisiae ADP + phosphate
-
 ?
5.6.2.3 ATP + H2O 5' to 3' DNA helicase. The ATPase/helicase activity of Rrm3p is required for its role in telomeric and subtelomeric DNA replication. Because Rrm3p is telomere-associated in vivo, it likely has a direct role in telomere replication Saccharomyces cerevisiae ADP + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.2.3 5' to 3' DNA helicase
-
 Saccharomyces cerevisiae
5.6.2.3 Rrm3p
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
5.6.2.3 37
-
 assay at Saccharomyces cerevisiae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
5.6.2.3 7.6
-
 assay at Saccharomyces cerevisiae