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Literature summary extracted from

  • Chappell, S.; Daly, L.; Morgan, K.; Guetta-Baranes, T.; Roca, J.; Rabinovich, R.; Lotya, J.; Millar, A.B.; Donnelly, S.C.; Keatings, V.; MacNee, W.; Stolk, J.; Hiemstra, P.S.; Miniati, M.; Monti, S.; OConnor, C.M.; Kalsheker, N.
    Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD (2008), Eur. Respir. J., 32, 931-937.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.3.2.9 medicine there is no association of EPHX1 gene variation with susceptibility to chronic obstructive pulmonary disease or disease severity Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.2.2 genes gclC and gclM, genotyping in healthy individuals and chronic obstructive pulmonary disease patients Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.3.2.9 microsome
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.2 additional information Homo sapiens GCL activity is not associated with susceptibility to chronic obstructive pulmonary disease patients or disease severity, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.3.2.9 Homo sapiens
-
-
-
6.3.2.2 Homo sapiens
-
 healthy individuals and chronic obstructive pulmonary disease patients, genes gclC and gclM encoding the two subunits of the enzyme
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.2.2 lung
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.3.2.9 cis-stilbene oxide + H2O
-
 Homo sapiens (1R,2R)-1,2-diphenylethane-1,2-diol
-
 ?
6.3.2.2 additional information GCL activity is not associated with susceptibility to chronic obstructive pulmonary disease patients or disease severity, overview Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.3.2.9 EPHX1
-
 Homo sapiens
6.3.2.2 GCL
-
 Homo sapiens