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Literature summary extracted from

  • MacLeod, H.; Bhasin, N.; Wetzler, L.M.
    Role of protein tyrosine kinase and Erk1/2 activities in the Toll-like receptor 2-induced cellular activation of murine B cells by neisserial porin (2008), Clin. Vaccine Immunol., 15, 630-637.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.10.1 PorB PorB from Neisseria meningitidis is able to induce protein tyrosine kinase activity Mus musculus

Application

EC Number Application Comment Organism
2.7.10.1 additional information B-cell proliferation and the induction of increased surface expression of costimulatory ligand CD86 by PorB are dependent on PTK activity and not Erk1/2 activation Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.10.1 genistein
-
 Mus musculus
2.7.10.1 Herbimycin
-
 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.1 Mus musculus
-
 strains C3H/HeJ and C57BL/6
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.1 spleen in B-cells of LPS-hyporesponsive strains C3H/HeJ, C57BL/6, and TLR2-deficient mice Mus musculus
-

Synonyms

EC Number Synonyms Comment Organism
2.7.10.1 Protein tyrosine kinase
-
 Mus musculus
2.7.10.1 PTK
-
 Mus musculus