Literature summary extracted from

Biran, V.; Cochois, V.; Karroubi, A.; Arrang, J.M.; Charriaut-Marlangue, C.; Heron, A.
Stroke induces histamine accumulation and mast cell degranulation in the neonatal rat brain (2008), Brain Pathol., 18, 1-9.

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.1.22	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
4.1.1.22	brain	the enzyme is not expressed after ischemic infarct	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.1.22	L-histidine	-	Rattus norvegicus	histamine + CO2	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
4.1.1.22	pyridoxal 5'-phosphate	-	Rattus norvegicus

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Release 2023.1 (January 2023)