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Literature summary extracted from

  • Aubele, M.; Walch, A.K.; Ludyga, N.; Braselmann, H.; Atkinson, M.J.; Luber, B.; Auer, G.; Tapio, S.; Cooke, T.; Bartlett, J.M.
    Prognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients (2008), Br. J. Cancer, 99, 1089-1095.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.7.10.2 medicine PTK6 may serve as a future target for the development of novel treatments in breast cancer Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.10.2 cytoplasm
-
 Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.10.2 ATP + [protein]-L-tyrosine Homo sapiens
-
 ADP + [protein]-L-tyrosine phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.10.2 Homo sapiens Q13882
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.10.2 breast cancer cell
-
 Homo sapiens
-
2.7.10.2 T-47D cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.10.2 ATP + [protein]-L-tyrosine
-
 Homo sapiens ADP + [protein]-L-tyrosine phosphate
-
 ?
2.7.10.2 ATP + [Sam68]-L-tyrosine
-
 Homo sapiens ADP + [Sam68]-L-tyrosine phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.10.2 breast tumour kinase
-
 Homo sapiens
2.7.10.2 Brk
-
 Homo sapiens
2.7.10.2 protein tyrosine kinase 6
-
 Homo sapiens
2.7.10.2 PTK6
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.10.2 ATP
-
 Homo sapiens