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Literature summary extracted from

  • Brahmachary, P.; Wang, G.; Benoit, S.L.; Weinberg, M.V.; Maier, R.J.; Hoover, T.R.
    The human gastric pathogen Helicobacter pylori has a potential acetone carboxylase that enhances its ability to colonize mice (2008), BMC Microbiol., 8, 14.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
6.4.1.6 medicine inactivation of operon acxABC encoding acetone carboxylase with a chloramphenicol resistance cassette. In mouse colonization studies the numbers of Helicobacter pylori recovered from mice inoculated with the acxB:cat mutant are generally one to two orders of magnitude lower than those recovered from mice inoculated with the parental strain Helicobacter pylori

Protein Variants

EC Number Protein Variants Comment Organism
6.4.1.6 additional information inactivation of operon acxABC encoding acetone carboxylase with a chloramphenicol resistance cassette. In mouse colonization studies the numbers of Helicobacter pylori recovered from mice inoculated with the acxB:cat mutant are generally one to two orders of magnitude lower than those recovered from mice inoculated with the parental strain Helicobacter pylori

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.4.1.6 additional information Helicobacter pylori operon acxABC encoding acetone carboxylase is involved in survival of the bacterium in stomach ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.6 Helicobacter pylori
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 mouse-adapted strain SSI
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.6 additional information operon acxABC encoding acetone carboxylase is involved in survival of the bacterium in stomach Helicobacter pylori ?
-
 ?