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Literature summary extracted from

  • Efrat, M.; Rosenblat, M.; Mahmood, S.; Vaya, J.; Aviram, M.
    Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: in vitro and in vivo studies (2009), Atherosclerosis, 202, 461-469.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.2 di-oleoyl phosphatidylcholine 2.6 mM di-oleoyl phosphatidylcholine stimulates arylesterase activity of PON1 3.5fold Mus musculus
3.1.8.1 di-oleoyl phosphatidylcholine 2.6 mM di-oleoyl phosphatidylcholine stimulates arylesterase activity of PON1 3.5fold Mus musculus

General Stability

EC Number General Stability Organism
3.1.1.2 addition of di-oleoyl phosphatidylcholine to serum stabilizes PON1 activity and protects PON1 from nitrilotriacetic acid-induced inactivation Mus musculus
3.1.8.1 addition of di-oleoyl phosphatidylcholine to serum stabilizes PON1 activity and protects PON1 from nitrilotriacetic acid-induced inactivation Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.2 Mus musculus P52430
-
-
3.1.8.1 Mus musculus P52430
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.2 serum
-
 Mus musculus
-
3.1.8.1 serum
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.2 phenyl acetate + H2O
-
 Mus musculus phenol + acetate
-
 ?
3.1.8.1 paraoxon + H2O
-
 Mus musculus diethylphosphate + 4-nitrophenol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.8.1 paraoxonase 1
-
 Mus musculus
3.1.8.1 PON1
-
 Mus musculus