Literature summary extracted from

Panagiotou, G.; Andersen, M.R.; Grotkjaer, T.; Regueira, T.B.; Nielsen, J.; Olsson, L.
Studies on the production of fungal polyketides in Aspergillus nidulans using systems biology tools (2009), Appl. Environ. Microbiol., 75, 2212-2220.

Application

EC Number	Application	Comment	Organism
2.3.1.165	biotechnology	production of 6-methylsalicylic acid which is used as human pharmaceutical	Penicillium griseofulvum
2.3.1.165	medicine	production of 6-methylsalicylic acid which is used as human pharmaceutical	Penicillium griseofulvum
4.1.2.9	pharmacology	polyketide natural products play an important role in the treatment of a wide range of human physiological disorders	Aspergillus nidulans

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.3.1.165	expressed in Aspergillus nidulans	Penicillium griseofulvum
4.1.2.9	-	Aspergillus nidulans

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4.1.2.9	D-Xylulose 5-phosphate + phosphate	Aspergillus nidulans	-	Acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.165	Penicillium griseofulvum	-	-	-
4.1.2.9	Aspergillus nidulans	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.2.9	D-Xylulose 5-phosphate + phosphate	-	Aspergillus nidulans	Acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.3.1.165	6-methylsalicylic acid synthase	-	Penicillium griseofulvum
2.3.1.165	6-MSA synthase	-	Penicillium griseofulvum
4.1.2.9	phosphoketolase	-	Aspergillus nidulans
4.1.2.9	XPK	-	Aspergillus nidulans
4.1.2.9	XpkA	-	Aspergillus nidulans
4.1.2.9	xylulose-5-phosphate phosphoketolase	-	Aspergillus nidulans

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Release 2023.1 (January 2023)