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Literature summary extracted from

  • Wuebbeler, J.H.; Bruland, N.; Kretschmer, K.; Steinbuechel, A.
    Novel pathway for catabolism of the organic sulfur compound 3,3-dithiodipropionic acid via 3-mercaptopropionic acid and 3-Sulfinopropionic acid to propionyl-coenzyme A by the aerobic bacterium Tetrathiobacter mimigardefordensis strain DPN7 (2008), Appl. Environ. Microbiol., 74, 4028-4035.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
4.2.1.3 additional information transposon mutagenesis. In one disulfide 3,3’-dithiodipropionic acid (DTDP)-negative (Jhw13b) and one DTDP-leaky (JhwAA14) mutant, Tn5::mob is mapped in a gene encoding a putative bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase (AcnB, EC 4.2.1.3). AcnB dehydrates 2-methylcitric acid to 2-methyl-cis-aconitic acid and subsequently hydrates it to 2-methylisocitric acid Advenella mimigardefordensis
4.2.1.99 additional information transposon mutagenesis. In one disulfide 3,3’-dithiodipropionic acid (DTDP)-negative (Jhw13b) and one DTDP-leaky (JhwAA14) mutant, Tn5::mob is mapped in a gene encoding a putative bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase (AcnB, EC 4.2.1.3). AcnB dehydrates 2-methylcitric acid to 2-methyl-cis-aconitic acid and subsequently hydrates it to 2-methylisocitric acid Advenella mimigardefordensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.13.1.4 3-sulfinopropanoyl-CoA + H2O Advenella mimigardefordensis
-
 propanoyl-CoA + sulfite
-
 ?
3.13.1.4 3-sulfinopropanoyl-CoA + H2O Advenella mimigardefordensis DPN7
-
 propanoyl-CoA + sulfite
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.13.1.4 Advenella mimigardefordensis
-
-
-
3.13.1.4 Advenella mimigardefordensis DPN7
-
-
-
4.2.1.3 Advenella mimigardefordensis B3TZE0
-
-
4.2.1.3 Advenella mimigardefordensis DPN7T B3TZE0
-
-
4.2.1.99 Advenella mimigardefordensis B3TZE0
-
-
4.2.1.99 Advenella mimigardefordensis DPN7T B3TZE0
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.13.1.4 3-sulfinopropanoyl-CoA + H2O
-
 Advenella mimigardefordensis propanoyl-CoA + sulfite
-
 ?
3.13.1.4 3-sulfinopropanoyl-CoA + H2O
-
 Advenella mimigardefordensis DPN7 propanoyl-CoA + sulfite
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.13.1.4 Desulfinase
-
 Advenella mimigardefordensis
4.2.1.3 Aconitate hydratase bifunctional enzyme: aconitate hydratase 2/2-methylisocitrate dehydratase Advenella mimigardefordensis
4.2.1.99 2/2-methylisocitrate dehydratase bifunctional enzyme: aconitate hydratase, 2/2-methylisocitrate dehydratase Advenella mimigardefordensis