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Literature summary extracted from

  • Varkonyi, J.; Karadi, I.; Szocs, K.; Sugar, I.; Sapi, Z.; Marschalko, M.; Pallinger, E.; Darvas, Z.; Falus, A.
    Loss of histidine decarboxylase as a marker of malignant transformation and dedifferentiation of B-cells infiltrating the skin. A case report of a therapy-resistant multiple myeloma complicated by skin infiltration (2008), Acta Oncol., 47, 458-461.
    View publication on PubMed

Application

EC Number Application Comment Organism
4.1.1.22 medicine loss of HDC is a marker of malignant transformation and dedifferentiation of B-cells infiltrating the skin Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.22 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.22 B-lymphocyte
-
 Homo sapiens
-
4.1.1.22 bone marrow
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.22 L-histidine
-
 Homo sapiens histamine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.22 HDC
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.22 pyridoxal 5'-phosphate
-
 Homo sapiens