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Literature summary extracted from

  • Heerschap, A.; Kan, H.E.; Nabuurs, C.I.; Renema, W.K.; Isbrandt, D.; Wieringa, B.
    In vivo magnetic resonance spectroscopy of transgenic mice with altered expression of guanidinoacetate methyltransferase and creatine kinase isoenzymes (2007), Subcell. Biochem., 46, 119-148.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.1.1.2 medicine GAMT deficiency in mouse is associated with increased neonatal mortality, muscular hypotonia, decreased male fertility and a non-leptin-mediated life-long reduction in body weight due to reduced body fat mass Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.2 S-adenosyl-L-methionine + guanidinoacetate Mus musculus
-
 S-adenosyl-L-homocysteine + creatine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.2 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.2 brain
-
 Mus musculus
-
2.1.1.2 heart
-
 Mus musculus
-
2.1.1.2 liver
-
 Mus musculus
-
2.1.1.2 pancreas
-
 Mus musculus
-
2.1.1.2 skeletal muscle
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.2 S-adenosyl-L-methionine + guanidinoacetate
-
 Mus musculus S-adenosyl-L-homocysteine + creatine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.2 GAMT
-
 Mus musculus
2.1.1.2 guanidinoacetate methyltransferase
-
 Mus musculus