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Literature summary extracted from

  • Marcos, J.; Shackleton, C.H.; Buddhikot, M.M.; Porter, F.D.; Watson, G.L.
    Cholesterol biosynthesis from birth to adulthood in a mouse model for 7-dehydrosterol reductase deficiency (Smith-Lemli-Opitz syndrome) (2007), Steroids, 72, 802-808.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
1.3.1.21 medicine a 7-dehydrosterol reductase deficiency is known as Smith-Lemli-Opitz syndrome Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.21 Mus musculus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.21 cholesta-5,7-dien-3beta-ol + NADPH
-
 Mus musculus cholesterol + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.21 3beta-hydroxysterol-DELTA7-reductase
-
 Mus musculus
1.3.1.21 Dhcr7
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.21 NADPH
-
 Mus musculus