Literature summary extracted from

Okamoto, K.; Eger, B.T.; Nishino, T.; Pai, E.F.; Nishino, T.
Mechanism of inhibition of xanthine oxidoreductase by allopurinol: crystal structure of reduced bovine milk xanthine oxidoreductase bound with oxipurinol (2008), Nucleosides Nucleotides Nucleic Acids, 27, 888-893.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
1.17.1.4	reduced enzyme in complex with oxipurinol at 2.0 A resolution. Electron density is observed between the N2 nitrogen atom of oxipurinol and the molybdenum atom of the molybdopterin cofactor. Oxipurinol forms hydrogen bonds with residues E802, R880, and E1261	Bos taurus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.17.1.4	Oxipurinol	crystal structure of reduced enzyme in complex with oxipurinol at 2.0 A resolution. Electron density is observed between the N2 nitrogen atom of oxipurinol and the molybdenum atom of the molybdopterin cofactor. Oxipurinol forms hydrogen bonds with residues E802, R880, and E1261	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.17.1.4	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.17.1.4	milk	-	Bos taurus	-

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.17.1.4	molybdopterin	in the crystal structure of reduced enzyme in complex with oxipurinol at 2.0 A resolution, electron density is observed between the N2 nitrogen atom of oxipurinol and the molybdenum atom of the molybdopterin cofactor	Bos taurus

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Release 2023.1 (January 2023)