EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.18.1 | 6-hydroxyapigenin | 5,6,7-trihydroxyflavone, high inhibitory effects on tyrosinase. Acts as a cofactor to monophenolase | Agaricus bisporus | |
1.14.18.1 | 6-hydroxygalangin | 5,6,7-trihydroxyflavone, high inhibitory effects on tyrosinase. Acts as a cofactor to monophenolase | Agaricus bisporus | |
1.14.18.1 | 6-hydroxykaempferol | 5,6,7-trihydroxyflavone, high inhibitory effects on tyrosinase. Acts as a cofactor to monophenolase. competitive inhibitor | Agaricus bisporus | |
1.14.18.1 | baicalein | 5,6,7-trihydroxyflavone, high inhibitory effects on tyrosinase. Acts as a cofactor to monophenolase | Agaricus bisporus | |
1.14.18.1 | kaempferol | - |
Agaricus bisporus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.14.18.1 | copper | - |
Agaricus bisporus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.18.1 | Agaricus bisporus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.18.1 | commercial preparation | - |
Agaricus bisporus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.14.18.1 | 3320 | - |
- |
Agaricus bisporus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.18.1 | L-dopa + 1/2 O2 | - |
Agaricus bisporus | L-dopaquinone + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.18.1 | tyrosinase | - |
Agaricus bisporus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.18.1 | 0.148 | - |
6-hydroxykaempferol | a competitive inhibitor of tyrosinase, L-DOPA as a substrate | Agaricus bisporus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.14.18.1 | 0.124 | - |
- |
Agaricus bisporus | 6-hydroxykaempferol | |
1.14.18.1 | 0.182 | - |
- |
Agaricus bisporus | 6-hydroxygalangin | |
1.14.18.1 | 0.193 | - |
- |
Agaricus bisporus | 6-hydroxyapigenin | |
1.14.18.1 | 0.262 | - |
- |
Agaricus bisporus | kaempferol | |
1.14.18.1 | 0.273 | - |
- |
Agaricus bisporus | baicalein |