Literature summary extracted from

Yoshida, H.; Beltran-Parrazal, L.; Butler, P.; Conti, M.; Charles, A.C.; Weiner, R.I.
Lowering cyclic adenosine-3',5'-monophosphate (cAMP) levels by expression of a cAMP-specific phosphodiesterase decreases intrinsic pulsatile gonadotropin-releasing hormone secretion from GT1 cells (2003), Mol. Endocrinol., 17, 1982-1990.

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.4.53	Mus musculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.4.53	GT1-1 cell	lowering cyclic adenosine-3',5'-monophosphate levels by expression of a cAMP-specific phosphodiesterase decreases intrinsic pulsatile gonadotropin-releasing hormone secretion from GT1 cells	Mus musculus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.4.53	adenosine 3',5'-cyclic phosphate + H2O	the enzyme is specific for cAMP	Mus musculus	adenosine 5'-phosphate	-	?

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Release 2023.1 (January 2023)