EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.23 | additional information | enzyme inhibition affects the binding of Hsp70 to RNA polymerase II, overview | Drosophila melanogaster |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.23 | ATP + RNA polymerase II C-terminal subunit | Drosophila melanogaster | Positive transcription elongation factor b is the major metazoan RNA polymerase II carboxyl-terminal domain Ser2 kinase, P-TEFb is critical for the maturation of RNA PolII into productive elongation in vivo, overview | ADP + phosphoylated RNA polymerase II C-terminal subunit | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.23 | Drosophila melanogaster | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.23 | Kc cell | - |
Drosophila melanogaster | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.23 | ATP + RNA polymerase II C-terminal subunit | Positive transcription elongation factor b is the major metazoan RNA polymerase II carboxyl-terminal domain Ser2 kinase, P-TEFb is critical for the maturation of RNA PolII into productive elongation in vivo, overview | Drosophila melanogaster | ADP + phosphoylated RNA polymerase II C-terminal subunit | - |
? | |
2.7.11.23 | ATP + RNA polymerase II C-terminal subunit | phosphorylation of Ser2 | Drosophila melanogaster | ADP + phosphoylated RNA polymerase II C-terminal subunit | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.11.23 | P-TEFb | - |
Drosophila melanogaster |
2.7.11.23 | Pol II CTD Ser2 kinase | - |
Drosophila melanogaster |
2.7.11.23 | positive transcription elongation factor b | - |
Drosophila melanogaster |
2.7.11.23 | RNA polymerase II carboxyl-terminal domain Ser2 kinase | - |
Drosophila melanogaster |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.23 | ATP | - |
Drosophila melanogaster |