Literature summary extracted from

Kim, W.; Yoon, J.H.; Jeong, J.M.; Cheon, G.J.; Lee, T.S.; Yang, J.I.; Park, S.C.; Lee, H.S.
Apoptosis-inducing antitumor efficacy of hexokinase II inhibitor in hepatocellular carcinoma (2007), Mol. Cancer Ther., 6, 2554-2562.

Application

EC Number	Application	Comment	Organism
2.7.1.1	medicine	HK II inhibitors may be therapeutically useful for the treatment of advanced infiltrative hypovascular hepatocellular carcinomas, which are growing in a hypoxic environment	Mus musculus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.1.1	3-Bromopyruvate	in mice treated with 3-bromopyruvate, mean tumor volumes and tumor volume growth are significantly reduced	Mus musculus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.1	Mus musculus	-	C3H mice implanted with MH134 cells	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.1.1	hexokinase II	-	Mus musculus
2.7.1.1	HK II	-	Mus musculus

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Release 2023.1 (January 2023)