Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Zhao, L.; Roche, B.M.; Wessale, J.L.; Kijtawornrat, A.; Lolly, J.L.; Shemanski, D.; Hamlin, R.L.
    Chronic xanthine oxidase inhibition following myocardial infarction in rabbits: effects of early versus delayed treatment (2008), Life Sci., 82, 495-502.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.17.3.2 allopurinol
-
 Oryctolagus cuniculus
1.17.3.2 febuxostat a potent non-purine, selective inhibitor of the enzyme Oryctolagus cuniculus
1.17.3.2 oxypurinol active metabolite of allopurinol Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.3.2 additional information Oryctolagus cuniculus chronic enzyme inhibition by allopurinol or febuxostat cannot prevent or treat the progression of congestive heart failure induced by coronary artery ligation in rabbits, overview ?
-
 ?
1.17.3.2 xanthine + H2O + O2 Oryctolagus cuniculus
-
 urate + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.17.3.2 Oryctolagus cuniculus
-
 male New Zealand White rabbits
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.3.2 heart enzyme expression is increased in the failing heart Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.3.2 additional information chronic enzyme inhibition by allopurinol or febuxostat cannot prevent or treat the progression of congestive heart failure induced by coronary artery ligation in rabbits, overview Oryctolagus cuniculus ?
-
 ?
1.17.3.2 xanthine + H2O + O2
-
 Oryctolagus cuniculus urate + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 production of superoxide radicals Oryctolagus cuniculus urate + H2O2
-
 ?