Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Miners, J.S.; Van Helmond, Z.; Chalmers, K.; Wilcock, G.; Love, S.; Kehoe, P.G.
    Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy (2006), J. Neuropathol. Exp. Neurol., 65, 1012-1021.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.11 thiorphan
-
Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.11 97000
-
-
Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.11 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.11 brain
-
Homo sapiens
-
3.4.24.11 hippocampus
-
Homo sapiens
-
3.4.24.11 kidney
-
Homo sapiens
-
3.4.24.11 lung
-
Homo sapiens
-
3.4.24.11 additional information in cerebrocortical blood vessels and in pyramidal neurons Homo sapiens
-
3.4.24.11 parenchyma
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.11 additional information hydrolysis of polypeptides between hydrophobic residues Homo sapiens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.11 NEP, enkephalinase, neutrophil cluster-differentiation antigen 10, common acute lymphoblastic leukemia antigen
-
Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.11 7.4
-
-
Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.4.24.11 6.5 7.5
-
Homo sapiens