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Literature summary extracted from

  • Costi, R.; Di Santo, R.; Artico, M.; Miele, G.; Valentini, P.; Novellino, E.; Cereseto, A.
    Cinnamoyl compounds as simple molecules that inhibit p300 histone acetyltransferase (2007), J. Med. Chem., 50, 1973-1977.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.48 1,7-bis(3-bromo-4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
-
 Homo sapiens
2.3.1.48 2,6-bis(3-bromo-4-hydroxybenzylidene)cyclohexanone
-
 Homo sapiens
2.3.1.48 curcumin
-
 Homo sapiens
2.3.1.48 Lys-CoA
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.48 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.48 HeLa cell
-
 Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
2.3.1.48 HAT
-
 Homo sapiens
2.3.1.48 histone acetyltransferase
-
 Homo sapiens
2.3.1.48 p300
-
 Homo sapiens

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.3.1.48 0.005
-
-
 Homo sapiens 1,7-bis(3-bromo-4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
2.3.1.48 0.03
-
-
 Homo sapiens Lys-CoA
2.3.1.48 0.033
-
-
 Homo sapiens 2,6-bis(3-bromo-4-hydroxybenzylidene)cyclohexanone
2.3.1.48 0.4
-
 value above 0.4 Homo sapiens curcumin