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Literature summary extracted from

  • Jongejan, A.; Jongejan, J.A.; Hagen, W.R.
    Direct hydride transfer in the reaction mechanism of quinoprotein alcohol dehydrogenases: a quantum mechanical investigation (2001), J. Comput. Chem., 22, 1732-1749.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.1.2.7 Ca2+ required for activity, functional role analysis, overview Methylorubrum extorquens
1.1.2.7 Ca2+ required for activity, functional role analysis, overview Methylophilus methylotrophus

Organism

EC Number Organism UniProt Comment Textmining
1.1.2.7 Methylophilus methylotrophus P38539 and P38540 P38539 (large subunit, alpha) and P38540 (small subunit, beta)
-
1.1.2.7 Methylorubrum extorquens P16027 and P14775 P16027 (large subunit, alpha) and P14775 (small subunit, beta)
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.1.2.7 a primary alcohol + 2 ferricytochrome cL = an aldehyde + 2 ferrocytochrome cL + 2 H+ catalytic mechanism, ping-pong kinetic schemes, and transition state structures, analysis by ab initio quantum mechanical methods, hydride transfer from the Calpha-position of the substrate alcohol or aldehyde directly to the C-5 carbon of PQQ is energetically feasible, detailed overview Methylorubrum extorquens
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.2.7 additional information oxidation of alcohols by direct hydride transfer to the pyrroloquinoline quinone cofactor Methylorubrum extorquens ?
-
 ?
1.1.2.7 additional information oxidation of alcohols by direct hydride transfer to the pyrroloquinoline quinone cofactor, catalytic mechanism, ping-pong kinetic schemes, and transition state structures, analysis by ab initio quantum mechanical methods, hydride transfer from the Calpha-position of the substrate alcohol or aldehyde directly to the C-5 carbon of PQQ is energetically feasible, detailed overview Methylophilus methylotrophus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.2.7 MDH
-
 Methylorubrum extorquens
1.1.2.7 MDH
-
 Methylophilus methylotrophus
1.1.2.7 methanol dehydrogenase
-
 Methylorubrum extorquens
1.1.2.7 methanol dehydrogenase
-
 Methylophilus methylotrophus
1.1.2.7 QH-ADH
-
 Methylorubrum extorquens
1.1.2.7 QH-ADH
-
 Methylophilus methylotrophus
1.1.2.7 quinohemoprotein alcohol dehydrogenase
-
 Methylorubrum extorquens
1.1.2.7 quinohemoprotein alcohol dehydrogenase
-
 Methylophilus methylotrophus
1.1.2.7 quinoprotein alcohol dehydrogenase
-
 Methylorubrum extorquens
1.1.2.7 quinoprotein alcohol dehydrogenase
-
 Methylophilus methylotrophus
1.1.5.5 MDH
-
-
1.1.5.5 methanol dehydrogenase
-
-
1.1.5.5 quinohemoprotein alcohol dehydrogenase
-
-

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.2.7 pyrroloquinoline quinone i.e. 2,7,9-tricarboxy-1H-pyrrolo[2,3-f]quinoline-4,5-dione, PQQ, structures of anionic PQQ, neutral PQQ, and reduced PQQ, overview Methylorubrum extorquens
1.1.2.7 pyrroloquinoline quinone i.e. 2,7,9-tricarboxy-1H-pyrrolo[2,3-f]quinoline-4,5-dione, PQQ, structures of anionic PQQ, neutral PQQ, and reduced PQQ, overview Methylophilus methylotrophus