Literature summary extracted from

Antczak, C.; Shum, D.; Escobar, S.; Bassit, B.; Kim, E.; Seshan, V.E.; Wu, N.; Yang, G.; Ouerfelli, O.; Li, Y.M.; Scheinberg, D.A.; Djaballah, H.
High-throughput identification of inhibitors of human mitochondrial peptide deformylase (2007), J. Biomol. Screen., 12, 521-535.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.5.1.88	2',2'-bisepigallocatechin monogallate	-	Homo sapiens
3.5.1.88	3-methoxycatechol	-	Homo sapiens
3.5.1.88	7,8-dihydroxyflavone	-	Homo sapiens
3.5.1.88	actinonin	-	Homo sapiens
3.5.1.88	chloranil	-	Homo sapiens
3.5.1.88	epigallocatechin 3,5-digallate	-	Homo sapiens
3.5.1.88	epitheaflavin monogallate	-	Homo sapiens
3.5.1.88	hematein	-	Homo sapiens
3.5.1.88	hematoxylin	-	Homo sapiens
3.5.1.88	irigenol	-	Homo sapiens
3.5.1.88	additional information	development of a high-throughput assay to screen for inhibitors	Homo sapiens
3.5.1.88	purpurogallin	-	Homo sapiens
3.5.1.88	pyrogallin	-	Homo sapiens
3.5.1.88	quinalizarin	-	Homo sapiens
3.5.1.88	theaflavin	-	Homo sapiens
3.5.1.88	theaflavin monogallate	-	Homo sapiens
3.5.1.88	thiram	-	Homo sapiens

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.5.1.88	mitochondrion	-	Homo sapiens	5739	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.5.1.88	Homo sapiens	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.5.1.88	-	Homo sapiens

Synonyms

EC Number	Synonyms	Comment	Organism
3.5.1.88	HsPDF	-	Homo sapiens

IC50 Value

EC Number	IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
3.5.1.88	0.0027	-	fluorescence polarization assay	Homo sapiens	hematoxylin
3.5.1.88	0.0041	-	fluorescence polarization assay	Homo sapiens	2',2'-bisepigallocatechin monogallate
3.5.1.88	0.0055	-	fluorescence polarization assay	Homo sapiens	actinonin
3.5.1.88	0.0057	-	fluorescence polarization assay	Homo sapiens	pyrogallin
3.5.1.88	0.0061	-	fluorescence polarization assay	Homo sapiens	theaflavin
3.5.1.88	0.0071	-	fluorescence polarization assay	Homo sapiens	theaflavin monogallate
3.5.1.88	0.0088	-	fluorescence polarization assay	Homo sapiens	purpurogallin
3.5.1.88	0.0089	-	fluorescence polarization assay	Homo sapiens	quinalizarin
3.5.1.88	0.012	-	fluorescence polarization assay	Homo sapiens	hematein
3.5.1.88	0.017	-	fluorescence polarization assay	Homo sapiens	7,8-dihydroxyflavone
3.5.1.88	0.017	-	fluorescence polarization assay	Homo sapiens	irigenol
3.5.1.88	0.029	-	fluorescence polarization assay	Homo sapiens	epitheaflavin monogallate
3.5.1.88	0.031	-	fluorescence polarization assay	Homo sapiens	3-methoxycatechol
3.5.1.88	0.038	-	fluorescence polarization assay	Homo sapiens	epigallocatechin 3,5-digallate
3.5.1.88	0.043	-	fluorescamine assay	Homo sapiens	thiram
3.5.1.88	0.048	-	fluorescence polarization assay	Homo sapiens	chloranil

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Release 2023.1 (January 2023)