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Literature summary extracted from

  • Blueschke, B.; Volkmer-Engert, R.; Schneider, E.
    Topography of the surface of the signal-transducing protein EIIAGlc that interacts with the MalK subunits of the maltose ATP-binding cassette transporter (MalFGK2) of Salmonella typhimurium (2006), J. Biol. Chem., 281, 12833-12840.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.5.2.1 EIIAGlc when glucose as preferred carbon source is transported, EIIAGlc becomes predominantly unphosphorylated and allosterically inhibits several permeases, including MalFGK2, which possesses a specific binding site in region III of EIIAGlc, in a process termed inducer exclusion involving the N-terminal part of the inhibitor, binding surface, overview Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.5.2.1 ATP + H2O + maltose/out Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + phosphate + maltose/in
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.5.2.1 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.5.2.1 ATP + H2O + maltose/out
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + phosphate + maltose/in
-
 ?
7.5.2.1 ATP + H2O + maltose/out signal-transducing protein EIIAGlc interacts with the MalK subunits of the maltose ATP-binding cassette transporter Salmonella enterica subsp. enterica serovar Typhimurium ADP + phosphate + maltose/in
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.5.2.1 MalFGK2
-
 Salmonella enterica subsp. enterica serovar Typhimurium