EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.4.3.21 | isoniazid | 0.2 mM, 42% inhibition of dimeric enzyme, 39% inhibition of tetrameric enzyme | Mycobacterium sp. | |
1.4.3.21 | KCl | 100 mM, 88% inhibition of dimeric and tetrameric enzyme | Mycobacterium sp. | |
1.4.3.21 | additional information | no effect: DTT or EDTA at 1 mM, 1,4-diamino-2-butanone, sodium azide or KCN | Mycobacterium sp. | |
1.4.3.21 | NaCl | 100 mM, 88% inhibition of dimeric and tetrameric enzyme | Mycobacterium sp. | |
1.4.3.21 | o-phenylenediamine | 0.2 mM, 33% inhibition of dimeric enzyme, 26% inhibition of tetrameric enzyme | Mycobacterium sp. | |
1.4.3.21 | Semicarbazide | 0.2 mM, 49% inhibition of dimeric enzyme, 45% inhibition of tetrameric enzyme | Mycobacterium sp. |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.4.3.21 | 0.0045 | - |
benzylamine | dimeric enzyme | Mycobacterium sp. | |
1.4.3.21 | 0.005 | - |
benzylamine | tetrameric enzyme | Mycobacterium sp. |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.4.3.21 | copper | the purified enzyme contains 2.39 mol of copper per mol of subunit | Mycobacterium sp. |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.4.3.21 | 75000 | - |
2 * 75000, SDS-PAGE | Mycobacterium sp. |
1.4.3.21 | 75000 | - |
4 * 75000, SDS-PAGE | Mycobacterium sp. |
1.4.3.21 | 150000 | - |
dimer, gel filtration | Mycobacterium sp. |
1.4.3.21 | 300000 | - |
tetramer, gel filtration | Mycobacterium sp. |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.4.3.21 | Mycobacterium sp. | - |
- |
- |
1.4.3.21 | Mycobacterium sp. DSM 3803 / JC1 | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.4.3.21 | - |
Mycobacterium sp. |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.4.3.21 | culture condition:benzylamine-grown cell | - |
Mycobacterium sp. | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.4.3.21 | 3.1 | - |
tetrameric enzyme | Mycobacterium sp. |
1.4.3.21 | 6.7 | - |
dimeric enzyme | Mycobacterium sp. |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.4.3.21 | benzylamine + H2O + O2 | best oxidized substrate | Mycobacterium sp. | benzaldehyde + NH3 + H2O2 | - |
? | |
1.4.3.21 | benzylamine + H2O + O2 | best oxidized substrate | Mycobacterium sp. DSM 3803 / JC1 | benzaldehyde + NH3 + H2O2 | - |
? | |
1.4.3.21 | histamine + H2O + O2 | - |
Mycobacterium sp. | (imidazol-4-yl)acetaldehyde + NH3 + H2O2 | - |
? | |
1.4.3.21 | histamine + H2O + O2 | - |
Mycobacterium sp. DSM 3803 / JC1 | (imidazol-4-yl)acetaldehyde + NH3 + H2O2 | - |
? | |
1.4.3.21 | tyramine + H2O + O2 | - |
Mycobacterium sp. | 4-hydroxyphenylethanal + NH3 + H2O2 | - |
? | |
1.4.3.21 | tyramine + H2O + O2 | - |
Mycobacterium sp. DSM 3803 / JC1 | 4-hydroxyphenylethanal + NH3 + H2O2 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.4.3.21 | dimer | 2 * 75000, SDS-PAGE | Mycobacterium sp. |
1.4.3.21 | tetramer | 4 * 75000, SDS-PAGE | Mycobacterium sp. |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.4.3.21 | semicarbazide-sensitive amine oxidase | - |
Mycobacterium sp. |
1.4.3.21 | SSAO | - |
Mycobacterium sp. |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.4.3.21 | 7 | - |
specific activities of dimeric and tetrameric enzyme form in Tris buffer at pH 7.0 is about 6fold lower than those in phosphate buffer at same pH | Mycobacterium sp. |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.4.3.21 | additional information | no evidences of topaquinone cofactor involvement | Mycobacterium sp. |