Literature summary extracted from

Abd-El-haleem, D.; Amara, A.; Zaki, S.; Abulhamd, A.; Abulreesh, G.
Biosynthesis of biodegradable polyhydroxyalkanotes biopolymers in genetically modified yeasts (2007), Int. J. Environ. Sci. Technol., 4, 513-520.

No PubMed abstract available

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.1.1.36	gene phbB, functional expression of the phaABCRe operon containing genes phbA, phbB and phbC of the PHA biosynthetic pathway of Ralstonia eutropha, which encode beta-ketothiolase, NADPH-linked acetoacetyl-CoA reductase and PHA synthase, respectively, in Saccharomyces cerevisiae strain INVSc1/PHA1 and in non-convenient Kloeckera spp. strain KY1/PHA, reconstruction of the PHA biosynthetic pathway leading to accumulation of poly-3-hydroxybutyrate and copolymer poly-(3-hydroxybutyrate-co-poly-3-hydroxyvalerate), respectively, overview	Cupriavidus necator

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.1.1.36	(R)-3-hydroxybutyryl-CoA + NADPH + H+	Cupriavidus necator	-	3-oxobutyryl-CoA + NADP+	-	r

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.36	Cupriavidus necator	-	gene phbB	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.1.1.36	additional information	-	-	Cupriavidus necator

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.36	(R)-3-hydroxybutyryl-CoA + NADPH + H+	-	Cupriavidus necator	3-oxobutyryl-CoA + NADP+	-	r

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.1.36	NADPH-linked acetoacetyl-CoA reductase	-	Cupriavidus necator
1.1.1.36	PhbB	-	Cupriavidus necator

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.36	NADP+	-	Cupriavidus necator
1.1.1.36	NADPH	-	Cupriavidus necator

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Release 2023.1 (January 2023)