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Literature summary extracted from

  • Leonardi, R.; Zhang, Y.M.; Lykidis, A.; Rock, C.O.; Jackowski, S.
    Localization and regulation of mouse pantothenate kinase 2 (2007), FEBS Lett., 581, 4639-4644.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.33 palmitoylcarnitine activates Mus musculus
2.7.1.33 palmitoylcarnitine activates Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.33
-
 Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.33 acetyl-CoA
-
 Homo sapiens
2.7.1.33 acetyl-CoA
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.33 cytosol
-
 Mus musculus 5829
-
2.7.1.33 cytosol
-
 Homo sapiens 5829
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.33 Homo sapiens
-
-
-
2.7.1.33 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.33 brain expression of PanK2 is higher in human brain compared to mouse brain Mus musculus
-
2.7.1.33 brain expression of PanK2 is higher in human brain compared to mouse brain Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.33 ATP + pantothenate
-
 Homo sapiens ADP + (R)-4'-phosphopantothenate
-
 ?
2.7.1.33 ATP + pantothenate
-
 Mus musculus ADP + (R)-4-phosphopantothenate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.33 hPANK2
-
 Homo sapiens
2.7.1.33 mPanK2
-
 Mus musculus
2.7.1.33 pantothenate kinase 2
-
 Mus musculus
2.7.1.33 pantothenate kinase 2
-
 Homo sapiens

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.7.1.33 0.0000625
-
-
 Mus musculus acetyl-CoA
2.7.1.33 0.000125
-
-
 Homo sapiens acetyl-CoA