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Literature summary extracted from

  • Mueller, M.; Klein, I.; Kopacsi, S.; Remaley, A.T.; Rajnavoelgyi, E.; Sarkadi, B.; Varadi, A.
    Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstane stimulated membrane ATPase activity (2006), FEBS Lett., 580, 6139-6144.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
7.6.2.2 3-doxyl-17beta-hydroxy-5alpha-androstane stimulation of ATPase-activity arising from co-expression of isoforms ABCG5 and ABCG8 Homo sapiens
7.6.2.2 4-androstene-3,17-dione stimulation of ATPase-activity arising from co-expression of isoforms ABCG5 and ABCG8 Homo sapiens
7.6.2.2 5-androsten-3beta-ol-17-one stimulation of ATPase-activity arising from co-expression of isoforms ABCG5 and ABCG8 Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
7.6.2.2 co-expression of isoforms ABCG5 and ABCG8 in insect cells Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
7.6.2.2 additional information co-expression of isoforms ABCG5 and ABCG8 in insect cells results in presence of a vanadate-sensitive ATPase activity in the membrane Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.6.2.2 progesterone inhibition of ATPase-activity arising from co-expression of isoforms ABCG5 and ABCG8 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
7.6.2.2 Homo sapiens
-
 isoforms ABCG5 and ABCG8
-