EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.7 | arachidonate | - |
synthetic construct | |
3.4.21.7 | oleate | - |
synthetic construct | |
3.4.21.7 | stearate | - |
synthetic construct |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.4.21.7 | additional information | truncated plasmin variants. Miniplasmin (des-kringle 1-4 plasmin) contains the kringle 5 and the catalytic domain of plasmin, whereas microplasmin (des-kringle 1-5 plasmin) is composed of the catalytic domain only. Miniplasmin (des-kringle 1-4 plasmin) is as sensitive to fatty acids as plasmin, whereas the activity of microplasmin (des-kringle 1-5 plasmin) is not affected | synthetic construct |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.7 | arachidonate | - |
synthetic construct | |
3.4.21.7 | oleate | - |
synthetic construct | |
3.4.21.7 | stearate | - |
synthetic construct |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.7 | 0.00589 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the absence of fatty acids | synthetic construct | |
3.4.21.7 | 0.00817 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.065 mM stearate | synthetic construct | |
3.4.21.7 | 0.01133 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.115 mM stearate | synthetic construct | |
3.4.21.7 | 0.01258 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.01 mM oleate | synthetic construct | |
3.4.21.7 | 0.02009 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.025 mM oleate | synthetic construct | |
3.4.21.7 | 0.02337 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.175 mM stearate | synthetic construct | |
3.4.21.7 | 0.02371 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.01 mM arachidonate | synthetic construct | |
3.4.21.7 | 0.02749 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.045 mM oleate | synthetic construct | |
3.4.21.7 | 0.04265 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.025 mM arachidonate | synthetic construct | |
3.4.21.7 | 0.05751 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.045 mM arachidonate | synthetic construct | |
3.4.21.7 | 0.05985 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.065 mM arachidonate | synthetic construct | |
3.4.21.7 | 0.07296 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.23 mM stearate | synthetic construct | |
3.4.21.7 | 0.1311 | - |
D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide | in the presence of 0.065 mM oleate | synthetic construct |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.7 | synthetic construct | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.7 | D-norleucyl-hexahydrotyrosyl-lysine-p-nitroanilide + H2O | - |
synthetic construct | ? | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.7 | 0.0002 | - |
stearate | in the presence of 0.23 mM stearate | synthetic construct | |
3.4.21.7 | 0.0007 | - |
stearate | in the presence of 0.175 mM stearate | synthetic construct | |
3.4.21.7 | 0.0012 | - |
stearate | in the presence of 0.115 mM stearate | synthetic construct | |
3.4.21.7 | 0.0025 | - |
stearate | in the presence of 0.065 mM stearate | synthetic construct |