Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Fragasso, G.; Spoladore, R.; Cuko, A.; Palloshi, A.
    Modulation of fatty acids oxidation in heart failure by selective pharmacological inhibition of 3-ketoacyl coenzyme-A thiolase (2007), Curr. Clin. Pharmacol., 2, 190-196.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.1.16 medicine 3-ketoacyl coenzyme-A thiolase inhibition could be a treatment for patients with heart failure Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.16 ranolazine
-
 Homo sapiens
2.3.1.16 trimetazidine
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.16 acyl-CoA + acetyl-CoA Homo sapiens
-
 CoA + 3-oxoacyl-CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.16 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.16 heart
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.16 acyl-CoA + acetyl-CoA
-
 Homo sapiens CoA + 3-oxoacyl-CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.16 3-KAT
-
 Homo sapiens
2.3.1.16 3-ketoacyl coenzyme-A thiolase
-
 Homo sapiens