Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Li, Y.; Mizutani, Y.; Shiraishi, T.; Nakamura, T.; Mikami, K.; Takaha, N.; Okihara, K.; Kawauchi, A.; Sakai, T.; Miki, T.
    The significance of the expression of dihydropyrimidine dehydrogenase in prostate cancer (2007), BJU Int., 99, 663-668.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.1 5-chloro-2,4-dihydroxypyridine potent inhibitor Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.1 DU-145 cell
-
 Homo sapiens
-
1.3.1.1 LNCaP cell
-
 Homo sapiens
-
1.3.1.1 prostate cancer cell
-
 Homo sapiens
-
1.3.1.1 prostate gland
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.1 5-fluorouracil + NADH + H+
-
 Homo sapiens 5-fluoro-5,6-dihydrouracil + NAD+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.1.1 dihydropyrimidine dehydrogenase
-
 Homo sapiens
1.3.1.1 DPD
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.1 NAD+
-
 Homo sapiens