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Literature summary extracted from

  • Mountassif, D.; Kabine, M.; Latruffe, N.; El Kebbaj, M.S.
    Prehibernation and hibernation effects on the D-3-hydroxybutyrate dehydrogenase of the heavy and light mitochondria from liver jerboa (Jaculus orientalis) and related metabolism (2007), Biochimie, 89, 1019-1028.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.30 mitochondrion light and heavy mitochondria, enzyme expression and activity is increased in heavy mitochondria in hibernating state, overview Jaculus orientalis 5739
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Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.30 (R)-3-hydroxybutanoate + NAD+ Jaculus orientalis
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 acetoacetate + NADH
-
 ?
1.1.1.30 additional information Jaculus orientalis a ketone body converting enzyme in mitochondria in liver jerboa, enzyme expression, activity and metabolism at different physiological states, overview ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.30 Jaculus orientalis
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.30 additional information the physiological states of the organism, i.e. euthermic, prehibernating, and hibernating, vary between in terms of ketone bodies, glucose and lipid levels, the enzyme might lead an important conformational change depending on the state, overview, enzyme expression is increased in hibernating state Jaculus orientalis
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.30 (R)-3-hydroxybutanoate + NAD+
-
 Jaculus orientalis acetoacetate + NADH
-
 ?
1.1.1.30 additional information a ketone body converting enzyme in mitochondria in liver jerboa, enzyme expression, activity and metabolism at different physiological states, overview Jaculus orientalis ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.30 BDH
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 Jaculus orientalis
1.1.1.30 D-3-hydroxybutyrate dehydrogenase
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 Jaculus orientalis

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.30 35
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 for heavy mitochondria Jaculus orientalis
1.1.1.30 40
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 for light mitochondria at euthermic state Jaculus orientalis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.30 8
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 assay at Jaculus orientalis

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.30 NAD+
-
 Jaculus orientalis