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Literature summary extracted from

  • Morash, A.J.; Kajimura, M.; McClelland, G.B.
    Intertissue regulation of carnitine palmitoyltransferase I (CPTI): mitochondrial membrane properties and gene expression in rainbow trout (Oncorhynchus mykiss) (2008), Biochim. Biophys. Acta, 1778, 1382-1389.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.21 malonyl-CoA
-
 Oncorhynchus mykiss

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 mitochondrial membrane
-
 Oncorhynchus mykiss 31966
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 palmitoyl-CoA + L-carnitine Oncorhynchus mykiss
-
 CoA + L-palmitoylcarnitine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Oncorhynchus mykiss
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.21 mitochondria are preparated Oncorhynchus mykiss

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 liver
-
 Oncorhynchus mykiss
-
2.3.1.21 muscle red, white and heart muscle Oncorhynchus mykiss
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.21 0.002
-
 CPT II, red muscle Oncorhynchus mykiss
2.3.1.21 0.0046
-
 CPT II, liver Oncorhynchus mykiss
2.3.1.21 0.0047
-
 CPT I, heart, plus 50 microM malonyl-CoA Oncorhynchus mykiss
2.3.1.21 0.0054
-
 CPT I, liver, plus 50 microM malonyl-CoA Oncorhynchus mykiss
2.3.1.21 0.0054
-
 CPT I, white muscle, plus 50 microM malonyl-CoA Oncorhynchus mykiss
2.3.1.21 0.0081
-
 CPT I, liver Oncorhynchus mykiss
2.3.1.21 0.0083
-
 CPT II, white muscle Oncorhynchus mykiss
2.3.1.21 0.0106
-
 CPT II, heart Oncorhynchus mykiss
2.3.1.21 0.0128
-
 CPT I, red muscle, plus 50 microM malonyl-CoA Oncorhynchus mykiss
2.3.1.21 0.0148
-
 CPT I, white muscle Oncorhynchus mykiss
2.3.1.21 0.0168
-
 CPT I, heart Oncorhynchus mykiss
2.3.1.21 0.0263
-
 CPT I, red muscle Oncorhynchus mykiss

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Oncorhynchus mykiss CoA + L-palmitoylcarnitine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.21 carnitine palmitoyltransferase I
-
 Oncorhynchus mykiss
2.3.1.21 carnitine palmitoyltransferase II
-
 Oncorhynchus mykiss
2.3.1.21 CPTi
-
 Oncorhynchus mykiss
2.3.1.21 CPTII
-
 Oncorhynchus mykiss

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.21 20
-
 activity assay at room temperature Oncorhynchus mykiss

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.21 7
-
 activity assay Oncorhynchus mykiss

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.3.1.21 0.000079
-
 CPT I, liver Oncorhynchus mykiss malonyl-CoA
2.3.1.21 0.00037
-
 CPT I, white muscle Oncorhynchus mykiss malonyl-CoA
2.3.1.21 0.0004
-
 CPT I, heart Oncorhynchus mykiss malonyl-CoA
2.3.1.21 0.00055
-
 CPT I, red muscle Oncorhynchus mykiss malonyl-CoA