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Literature summary extracted from

  • Guan, R.; Roderick, S.L.; Huang, B.; Cook, P.F.
    Roles of histidines 154 and 189 and aspartate 139 in the active site of serine acetyltransferase from Haemophilus influenzae (2008), Biochemistry, 47, 6322-6328.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
2.3.1.30 D139N Km (mM): 0.12 (acetyl-CoA), 160 (L-serine) Haemophilus influenzae
2.3.1.30 H154N Km (mM): 0.21 (acetyl-CoA), 0.6 (L-serine) Haemophilus influenzae
2.3.1.30 H154N/H189N Km (mM): 0.24 (acetyl-CoA), 27 (L-serine) Haemophilus influenzae
2.3.1.30 H189N Km (mM): 32 (L-serine) Haemophilus influenzae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.30 0.12
-
 acetyl-CoA mutant D139N Haemophilus influenzae
2.3.1.30 0.21
-
 acetyl-CoA mutant H154N Haemophilus influenzae
2.3.1.30 0.24
-
 acetyl-CoA mutant H154N/H189N Haemophilus influenzae
2.3.1.30 0.6
-
 L-serine mutant H154N Haemophilus influenzae
2.3.1.30 0.7
-
 acetyl-CoA
-
 Haemophilus influenzae
2.3.1.30 4.7
-
 L-serine
-
 Haemophilus influenzae
2.3.1.30 27
-
 L-serine mutant H154N/H189N Haemophilus influenzae
2.3.1.30 32
-
 L-serine mutant H189N Haemophilus influenzae
2.3.1.30 160
-
 L-serine mutant D139N Haemophilus influenzae

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.30 Haemophilus influenzae P43886
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.30 acetyl-CoA + L-serine
-
 Haemophilus influenzae CoA + O-acetyl-L-serine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.30 SAT
-
 Haemophilus influenzae
2.3.1.30 serine O-acetyltransferase
-
 Haemophilus influenzae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.30 25
-
 assay at Haemophilus influenzae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.30 7.3
-
 assay at Haemophilus influenzae