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Literature summary extracted from

  • Schuldt, L.; Weyand, S.; Kefala, G.; Weiss, M.S.
    Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of tetrahydrodipicolinate-N-succinyltransferase (Rv1201c) from Mycobacterium tuberculosis (2008), Acta Crystallogr. Sect. F, 64, 863-866.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.117 expressed in Escherichia coli Mycobacterium tuberculosis

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.3.1.117 crystallized in the cubic space group I23 or I213. Diffraction data analysis indicates the presence of five molecules per asymmetric unit. Data exhibit icosahedral point-group symmetry. Enzyme might assembles into a 60-mer exhibiting 235 point-group symmetry and crystallizes as such in space group I23. In this case, the combination of crystallographic and noncrystallographic symmetry elements results in an arrangement of the icosahedrons in the cubic crystal with one pentamer in the asymmetric unit. Another explanation is that the packing of the molecules itself mimics icosahedral symmetry. In this case both space groups I23 and I213 would be possible Mycobacterium tuberculosis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.117 100000
-
 gel filtration, homotrimer Mycobacterium tuberculosis

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.117 Mycobacterium tuberculosis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.117 using affinity chromatography and gel filtration Mycobacterium tuberculosis

Subunits

EC Number Subunits Comment Organism
2.3.1.117 homotrimer gel filtration Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
2.3.1.117 tetrahydrodipicolinate-N-succinyltransferase
-
 Mycobacterium tuberculosis