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Literature summary extracted from

  • Pluvinage, B.; de la Sierra-Gallay, I.L.; Martins, M.; Ragunathan, N.; Dupret, J.M.; Rodrigues-Lima, F.
    Crystallization and preliminary X-ray characterization of arylamine N-acetyltransferase C (BanatC) from Bacillus anthracis (2007), Acta Crystallogr. Sect. F, 63, 862-864.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.3.1.5 pharmacology NATs play an important role in the detoxication and, or bioactivation of numerous drugs and xenobiotics Bacillus anthracis

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.5 into the pET28a vector for expression in Escherichia coli BL21DE3 cells Bacillus anthracis

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.3.1.5 crystals diffract to 1.95 A resolution on a synchrotron source Bacillus anthracis

Protein Variants

EC Number Protein Variants Comment Organism
2.3.1.5 Y38F whereas wild-type BanatC proves difficult to crystallize, the mutant displaying the same enzymatic characterisics as the wild-type is found to crystallize and to diffract Bacillus anthracis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.5 34000
-
 determined by SDS-PAGE and Western Blot analysis Bacillus anthracis

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.5 Bacillus anthracis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.5 using HIS-select nickel resin Bacillus anthracis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.5 acetyl-CoA + sulfamethoxazole
-
 Bacillus anthracis ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.5 arylamine N-acetyltransferase C
-
 Bacillus anthracis
2.3.1.5 BanatC
-
 Bacillus anthracis
2.3.1.5 N-hydroxyarylamine O-acetyltransferase
-
 Bacillus anthracis
2.3.1.5 NAT
-
 Bacillus anthracis