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Literature summary extracted from

  • Dragutinovic, V.V.; Radovanovic, N.S.; Izrael-Zivkovic, L.T.; Vrvic, M.M.
    Detection of gelatinase B activity in serum of gastric cancer patients (2006), World J. Gastroenterol., 12, 105-109.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.35 1,10-phenanthroline
-
 Homo sapiens
3.4.24.35 EDTA
-
 Homo sapiens
3.4.24.35 TIMP-1 formation of proMMP-9/TIMP-1 complexes Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.35 extracellular
-
 Homo sapiens
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.35 Ca2+
-
 Homo sapiens
3.4.24.35 Zn2+
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.35 92000
-
 2 * 92000, pro-MMP-9, SDS-PAGE Homo sapiens
3.4.24.35 220000
-
 native PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.35 Gelatin + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.35 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.35 gastric cancer cell proteolytic activity and expression of gelatinase B in serum of gastric cancer patients and their correlation with the stage of the tumor Homo sapiens
-
3.4.24.35 serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.35 Gelatin + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.35 Gelatin + H2O gelatin zymography Homo sapiens ?
-
 ?
3.4.24.35 N-alpha-benzoyl-arginine p-nitroanilide + H2O i.e. BAPNA Homo sapiens N-alpha-benzoyl-Arg + 4-nitroaniline
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.24.35 dimer 2 * 92000, pro-MMP-9, SDS-PAGE Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.24.35 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.35 8.3
-
 assay at Homo sapiens