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Literature summary extracted from

  • Wallis, M.G.; Lankford, M.F.; Keller, S.R.
    Vasopressin is a physiological substrate for the insulin-regulated aminopeptidase IRAP (2007), Am. J. Physiol. Endocrinol. Metab., 293, E1092-E1102.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
3.4.11.3 additional information adipocytes and skeletal muscle cells of IRAP-/- mice do not process vasopressin and oxytocin from their N-terminus. In IRAP-/- mice, plasma vasopressin level is elevated twofold and vasopressin levels in mutant mice brains show a compensatory decrease Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.11.3 vasopressin + H2O Mus musculus vasopressin is a physiological substrate hydrolyzed vasopressin N-terminal processing ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.3 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.3 adipocyte
-
 Mus musculus
-
3.4.11.3 skeletal muscle
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.3 oxytocin + H2O
-
 Mus musculus ? N-terminal processing ?
3.4.11.3 vasopressin + H2O vasopressin is a physiological substrate Mus musculus hydrolyzed vasopressin N-terminal processing ?