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Literature summary extracted from

  • Tomasek, J.J.; Vaughan, M.B.; Kropp, B.P.; Gabbiani, G.; Martin, M.D.; Haaksma, C.J.; Hinz, B.
    Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity (2006), Wound Repair Regen., 14, 313-320.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.1.3.53 medicine myosin light chain phosphatase pathway is critical in regulating in vivo myofibroblast differentiation during wound healing and fibrocontractive diseases Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.53 calyculin
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.53 Rattus norvegicus
-
 Sprague-Dawley
-
3.1.3.53 Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.53 myofibroblast granuloma pouch model of granulation tissue, organ culture Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.53 myosin light-chain phosphate + H2O
-
 Rattus norvegicus myosin light-chain + phosphate
-
 ?
3.1.3.53 myosin light-chain phosphate + H2O
-
 Rattus norvegicus Sprague-Dawley myosin light-chain + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.53 MLCP
-
 Rattus norvegicus
3.1.3.53 [myosin-light-chain] phosphatase
-
 Rattus norvegicus