Literature summary extracted from

Cheng, L.; Zhou, R.; Reidel, E.J.; Sharkey, T.D.; Dandekar, A.M.
Antisense inhibition of sorbitol synthesis leads to up-regulation of starch synthesis without altering CO2 assimilation in apple leaves (2005), Planta, 220, 767-776.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.1.1.200	Greensleeves apple is transformed with a cDNA encoding aldose 6-phosphate reductase in the antisense orientation. Antisense expression of A6PR decreases A6PR activity in mature leaves to approximately 15-30% of the untransformed control. The antisense plants have lower concentrations of sorbitol but higher concentrations of sucrose and starch in mature leaves at both dusk and predawn	Malus domestica

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.1.1.200	additional information	Malus domestica	when sorbitol synthesis is decreased by antisense inhibition of A6PR expression, cytosolic FBPase activity in vivo is down-regulated to reduce the carbon flux to cytosol and starch synthesis in the chloroplast is consequently upregulated	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.200	Malus domestica	-	Greensleeves	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.200	additional information	when sorbitol synthesis is decreased by antisense inhibition of A6PR expression, cytosolic FBPase activity in vivo is down-regulated to reduce the carbon flux to cytosol and starch synthesis in the chloroplast is consequently upregulated	Malus domestica	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.1.1.200	A6PR	-	Malus domestica
1.1.1.200	S6PDH	-	Malus domestica
1.1.1.200	sorbitol-6-phosphate dehydrogenase	-	Malus domestica

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Release 2023.1 (January 2023)