Literature summary extracted from

Kasuya, F.; Igarashi, K.; Fukui, M.
Inhibition of a medium chain acyl-CoA synthetase involved in glycine conjugation by carboxylic acids (1996), Biochem. Pharmacol., 52, 1643-1646.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
6.2.1.2	2-Hydroxynaphthoic acid	competitive with respect to hexanoate	Bos taurus
6.2.1.2	2-Hydroxyoctanoic acid	competitive with respect to hexanoate	Bos taurus
6.2.1.2	4-methylsalicylic acid	competitive with respect to hexanoate	Bos taurus
6.2.1.2	salicylic acid	competitive with respect to hexanoate	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.2.1.2	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
6.2.1.2	liver	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.2.1.2	ATP + hexanoate + CoA	-	Bos taurus	AMP + diphosphate + hexanoyl-CoA	-	?

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Release 2023.1 (January 2023)