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Literature summary extracted from

  • Muccioli, G.G.; Xu, C.; Odah, E.; Cudaback, E.; Cisneros, J.A.; Lambert, D.M.; Lopez Rodriguez, M.L.; Bajjalieh, S.; Stella, N.
    Identification of a novel endocannabinoid-hydrolyzing enzyme expressed by microglial cells (2007), J. Neurosci., 27, 2883-2889.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.99 1,1-biphenyl-3-yl-carbamic acid cyclohexyl ester i.e. URB602 Mus musculus
3.5.1.99 methyl arachidonyl fluorophosphonate
-
 Mus musculus
3.5.1.99 additional information the microglial-specific isozyme is not inhibited by URB597, i.e. 3'-carbamoyl-biphenyl-3-ylcyclohexylcarbamate, and inhibitors of cyclooxygenases, lipooxygenases, and diacylglycerol lipases, overview Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.99 2-arachidonoylglycerol + H2O Mus musculus FAAH is responsible for approximately one-half of the 2-arachidonoylglycerol hydrolysis occurring in BV-2 cell homogenate ?
-
 ?
3.5.1.99 anandamide + H2O Mus musculus anandamide hydrolysis in BV-2 cells is entirely attributable to FAAH ethanolamine + arachidonic acid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.99 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.5.1.99 BV-2 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.99 2-arachidonoylglycerol + H2O FAAH is responsible for approximately one-half of the 2-arachidonoylglycerol hydrolysis occurring in BV-2 cell homogenate Mus musculus ?
-
 ?
3.5.1.99 anandamide + H2O anandamide hydrolysis in BV-2 cells is entirely attributable to FAAH Mus musculus ethanolamine + arachidonic acid
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.99 FAAH
-
 Mus musculus