Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Li, F.; Wu, N.; Su, R.B.; Zheng, J.Q.; Xu, B.; Lu, X.Q.; Cong, B.; Li, J.
    Involvement of phosphatidylcholine-selective phospholipase C in activation of mitogen-activated protein kinase pathways in imidazoline receptor antisera-selected protein (2006), J. Cell. Biochem., 98, 1615-1628.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.4.3 moxonidine incubation of CHO cells stably expressing human imidazoline receptor antisera-selected protein IRAS for 5 min can induce an upregulation of isoform PC-PLC activity and an increase in the accumulation of reaction product diacylglycerol Cricetulus griseus
3.1.4.3 rilmenidine incubation of CHO cells stably expressing human imidazoline receptor antisera-selected protein IRAS for 5 min can induce an upregulation of isoform PC-PLC activity and an increase in the accumulation of reaction product diacylglycerol Cricetulus griseus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.3 additional information Cricetulus griseus the signaling pathway of human imidazoline receptor antisera-selected protein IRAS in response to I1-imidazoline receptor agonists is coupled with the activation of isoform PC-PLC and its downstream signal transduction molecule ERK ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.3 Cricetulus griseus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.3 CHO cell stably expressing human imidazoline receptor antisera-selected protein IRAS Cricetulus griseus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.3 additional information the signaling pathway of human imidazoline receptor antisera-selected protein IRAS in response to I1-imidazoline receptor agonists is coupled with the activation of isoform PC-PLC and its downstream signal transduction molecule ERK Cricetulus griseus ?
-
 ?