Literature summary extracted from
Kanda, Y.; Imai-Nishiya, H.; Kuni-Kamochi, R.; Mori, K.; Inoue, M.; Kitajima-Miyama, K.; Okazaki, A.; Iida, S.; Shitara, K.; Satoh, M.
Establishment of a GDP-mannose 4,6-dehydratase (GMD) knockout host cell line: a new strategy for generating completely non-fucosylated recombinant therapeutics (2007), J. Biotechnol., 130, 300-310.
Application
EC Number |
Application |
Comment |
Organism |
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4.2.1.47 |
synthesis |
GMD knockout CHO cells are ideal host cells for the manufacture of completely non-fucosylated therapeutic antibodies and completely O-fucose-negative therapeutics as well |
Cricetulus griseus |
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
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4.2.1.47 |
Cricetulus griseus |
Q8K3X3 |
- |
- |