Literature summary extracted from

Forbes, C.D.; Toth, J.G.; Ozbal, C.C.; Lamarr, W.A.; Pendleton, J.A.; Rocks, S.; Gedrich, R.W.; Osterman, D.G.; Landro, J.A.; Lumb, K.J.
High-throughput mass spectrometry screening for inhibitors of phosphatidylserine decarboxylase (2007), J. Biomol. Screen., 12, 628-634.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
4.1.1.65	expressed in HEK 293F cells	Homo sapiens

General Stability

EC Number	General Stability	Organism
4.1.1.65	stable upon acid quenching with 69 mM HCl	Homo sapiens

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.1.1.65	additional information	DMSO has no discernable effect on product formation	Homo sapiens

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
4.1.1.65	0.09	-	phosphatidyl-L-serine	in 100 mM potassium phosphate, pH 6.8, 10 mM EDTA, and 0.05% Triton X-100	Homo sapiens

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
4.1.1.65	mitochondrion	-	Homo sapiens	5739	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.1.65	Homo sapiens	-	-	-

Storage Stability

EC Number	Storage Stability	Organism
4.1.1.65	-80°C, 72 h, remains stable	Homo sapiens

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.1.65	Phosphatidyl-L-serine	-	Homo sapiens	Phosphatidylethanolamine + CO2	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
4.1.1.65	PISD	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)