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Literature summary extracted from

  • Parks, Q.M.; Hobden, J.A.
    Polyphosphate kinase 1 and the ocular virulence of Pseudomonas aeruginosa (2005), Invest. Ophthalmol. Vis. Sci., 46, 248-251.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.4.1 complementation of the PPK1-deficient mutant strain PAOM5 by the wild-type PPK1 Pseudomonas aeruginosa

Protein Variants

EC Number Protein Variants Comment Organism
2.7.4.1 additional information the PPK1-deficient strain PAOM5, an isogenic mutant of strain PAO1, is significantly less virulent than either wild-type strain PAO1 or the complemented mutant, the loss of ocular virulence is probably due to the dysregulation of multiple genes, including those responsible for stress response, the PPK1-deficient mutant produces significantly less pyocyanin, phenotype, overview Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.4.1 ATP + (phosphate)n Pseudomonas aeruginosa PPK1 is essential for a successful ocular infection by the organism ADP + (phosphate)n+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.1 Pseudomonas aeruginosa
-
 cultured in mouse eyes
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.1 ATP + (phosphate)n
-
 Pseudomonas aeruginosa ADP + (phosphate)n+1
-
 ?
2.7.4.1 ATP + (phosphate)n PPK1 is essential for a successful ocular infection by the organism Pseudomonas aeruginosa ADP + (phosphate)n+1
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.4.1 polyphosphate kinase 1
-
 Pseudomonas aeruginosa
2.7.4.1 PPK1
-
 Pseudomonas aeruginosa

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.4.1 ATP
-
 Pseudomonas aeruginosa