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Literature summary extracted from

  • Juris, S.J.; Melnyk, R.A.; Bolcome, R.E.; Chan, J.; Collier, R.J.
    Cross-linked forms of the isolated N-terminal domain of the lethal factor are potent inhibitors of anthrax toxin (2007), Infect. Immun., 75, 5052-5058.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.24.83 fusion protein between lethal factor and the catalytic domain of diphtheria toxin is expressed in Escherichia coli BL21(DE3) cells Bacillus anthracis

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.83 C-terminal dimer of the protective antigen binding domain of anthrax lethal factor
-
 Bacillus anthracis
3.4.24.83 C-terminal trimer of the protective antigen binding domain of anthrax lethal factor
-
 Bacillus anthracis
3.4.24.83 N-terminal dimer of the protective antigen binding domain of anthrax lethal factor
-
 Bacillus anthracis
3.4.24.83 N-terminal trimer of the protective antigen binding domain of anthrax lethal factor
-
 Bacillus anthracis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.83 Bacillus anthracis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.83 mitogen-activated protein kinase + H2O
-
 Bacillus anthracis ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.83 lethal factor
-
 Bacillus anthracis